urban areas as infrastructure ages and water treatment systems disintegrate or are simply unable to keep up with population growth. Cholera is no respecter of international borders and is frequently passed between countries, requiring a coordinated and multilateral approach to preparedness and response. There are knock-on effects on care-seeking behaviours: households are prioritizing limited financial resources to buy food rather than pay for travel to a health facility. There are also reports of decreasing numbers of pregnant women presenting to give birth at health facilities, risking higher rates of maternal and neonatal deaths and mother-to-child transmission of HIV. Individuals requiring chronic care – such as those on ART and TB treatment, experience interruptions in life-saving therapy. HIV AND TB CO-INFECTION The region remains the global epicentre of the AIDS pandemic. In 2015, nine countries – Botswana, Lesotho, Malawi, Mozambique, Namibia, South Africa, Swaziland, Zambia and Zimbabwe - had adult HIV prevalence of over 10 per cent. At an estimated 28.8 per cent, Swaziland has the highest HIV prevalence in the world, followed by Botswana (23.4 per cent) and Lesotho (22.3 per cent). These countries are part of the 35 priority `Fast-Track’ countries of UNAIDS’ strategy 2016-2021 and for ending AIDS globally by 2030. Similarly, the region continues to face HIV/TB co-infection with TB remaining the leading cause of death among people living with HIV. For example, percentage of HIV positive patients with TB co-infection is 73 per cent in Swaziland, 72 per cent in Lesotho and 68 per cent in Zimbabwe. El Niño disruption of Adult HIV Prevalence Source: SADC 16